Cytotoxicity of Root Canal Disinfecting Agents against Stem Cells of Apical Papilla – A Review
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چکیده
The aim of this review was to systematically assess the literature on cytotoxicity of root canal irrigants and intracanal medicaments on stem cells of the apical papilla. A structured strategy was employed and 7 papers were identified. The papers were analysed for concentration of agent used, testing method and viability of stem cells of the apical papilla (SCAP). Irrigation protocols using a final revise of EDTA showed superior survival of SCAP. The results showed that the endodontic literature is inconsistent with regards to the effect of intracanal medicaments on SCAP. Further studies are recommended to determine the ideal disinfection regimen prior to regenerative endodontic strategries.
منابع مشابه
Evaluation of Cytotoxic Effects of Various Endodontic Irrigation Solutions on the Survival of Stem Cell of Human Apical Papilla
INTRODUCTION Root canal disinfection is an important step in regenerative endodontic treatments. An ideal irrigating solution must have high antimicrobial activity and minimum cytotoxicity. This study sought to assess the effect of some irrigating solutions on stem cells from the human apical papilla (SCAP) after different periods of exposure. METHODS AND MATERIALS Stem cells were isolated fr...
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